https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50112 Wed 28 Feb 2024 16:20:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53239 Wed 28 Feb 2024 15:57:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45158 N = 70) who had experienced a stroke between 5 months and 28 years ago were included in the cross-sectional study, along with age-matched controls (N = 70). We measured stress using both the Perceived Stress Scale and biological markers, and resilience using both the Brief Resilience Scale and the Connor-Davidson Resilience Scale. Stroke outcomes were assessed using the Stroke Impact Scale. We found that, compared with age-matched controls, stroke survivors reported greater levels of perceived stress, and lower levels of resilience. In stroke survivors, both perceived stress and resilience were independently associated with stroke outcomes in linear regression models. In particular, these relationships were observed for cognitive outcomes including mood, memory, and communication. The association between stress and stroke outcome did not differ across time post stroke. Given that resilience is a modifiable psychological construct, future research may consider whether strategies directed at enhancing resilience may improve recovery from stroke. Australia and New Zealand Clinical Trials Registry: ACTRN12617000736347.]]> Wed 26 Oct 2022 19:17:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44989 a priori, and separate searches were conducted for each concept. The methodology involved three main phases: data collection and filtering, development of a clinical vocabulary, and the development of an automatic clinical text processing engine to aid the process and identify the unique and common topics. The common themes from the intersection of the three concepts were identified. These were then reviewed, with particular reference to the top 30 articles identified as intersecting these concepts. Results: The search of the three concepts separately yielded 405,636 publications. Publications were filtered to include only human studies, generating 263,751 publications related to the concepts of neuroplasticity (n=6,498), stroke recovery (n=79,060), and learning (n=178,193). A cluster concept map (network graph) was generated from the results; indicating the concept nodes, strength of link between nodes, and the intersection between all three concepts. We identified 23 common themes (topics) and the top 30 articles that best represent the intersecting themes. A time-linked pattern emerged. Discussion and Conclusions: Our novel approach developed for this review allowed the identification of the common themes/topics that intersect the concepts of neuroplasticity, stroke recovery, and learning. These may be synthesised to advance a neuroscience-informed approach to stroke rehabilitation. We also identified gaps in available literature using this approach. These may help guide future targeted research.]]> Wed 26 Oct 2022 15:08:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45071 p = 0.06) or as a significant effect (ΔIGF-I, p = 0.03) after all the adjustments. Specifically, for each unit of PA, ΔIGF-I increased by 9.7 (95% CI 1,1−18.4) ng/mL after full adjustment. This supports the notion that pre-stroke PA is independently related to ΔIGF-I.]]> Wed 26 Oct 2022 12:29:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30085 Wed 24 Nov 2021 15:50:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46450 Wed 23 Nov 2022 14:17:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33097 Wed 19 Jan 2022 15:17:31 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32497 Wed 17 Nov 2021 16:32:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33094 Wed 17 Nov 2021 16:30:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35334 Wed 17 Nov 2021 16:28:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19715 Wed 12 Aug 2015 14:39:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14413 Wed 11 Apr 2018 14:45:30 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20679 Wed 11 Apr 2018 14:40:07 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19339  A, −1.0 years per allele, p = 0.042; rs35652124 A > G, −1.1 years per allele, p = 0.045; rs2886161 A > G, −1.2 years per allele, p = 0.021; rs1806649 G > A, +1.2 years per allele, p = 0.029). One of these (rs35652124) is a functional SNP located in the NFE2L2 promoter. No individual SNP was associated with risk of Parkinson’s disease. Conclusion: Our results support the hypothesis that variation in the NFE2L2 gene, encoding a central protein in the cellular protection against oxidative stress, may contribute to the pathogenesis of Parkinson’s disease. Functional studies are now needed to explore these results further.]]> Wed 11 Apr 2018 14:07:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28588 Wed 11 Apr 2018 12:59:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32689 Wed 10 Nov 2021 15:04:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49294 Wed 10 May 2023 13:55:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49280 Wed 10 May 2023 13:13:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33101 Wed 09 Feb 2022 15:58:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43925 Wed 05 Oct 2022 11:27:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33093 Wed 04 Sep 2019 09:56:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34623 Wed 04 Sep 2019 09:49:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33578 Wed 04 Sep 2019 09:48:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52178 Wed 04 Oct 2023 11:05:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49081 Wed 03 May 2023 16:22:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54067 Tue 30 Jan 2024 13:56:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38036 Tue 27 Jul 2021 15:08:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38037 Tue 27 Jul 2021 14:35:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38035 Tue 27 Jul 2021 13:32:27 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38034 Tue 27 Jul 2021 12:36:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54485 Tue 27 Feb 2024 15:11:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39822 0.8), and only 2 studies were able to externally validate their developed model. In general, models that performed well used large patient numbers, were tested on similar demographics, and used either nonlinear input transformations or a completely nonlinear model. Conclusion: Some models do show promise; however, there remains the question of whether the reported predictive success can continue to be replicated. Furthermore, clinical applicability and interpretation of predictive tools should be considered during development.]]> Tue 26 Jul 2022 11:57:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35674 Tue 22 Oct 2019 11:50:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33896 Tue 22 Jan 2019 14:21:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48324 Tue 14 Mar 2023 16:40:44 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43109 Tue 13 Sep 2022 13:22:36 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52391 Tue 10 Oct 2023 14:47:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43876 Tue 04 Oct 2022 12:35:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33464 To be intellectually challenged (energy-consuming activity and coordinating multiple input and output), Perceived therapeutic benefits (motor skills, cognitive skills, emotional and psychological responses), and Pros and cons with social integration (fellowship, competing with others, and instructor characteristics). From these categories, an overall theme was derived: The multifaceted layers of multimodal stimulation. Enjoying music, being part of a group with peers, a skilled instructor, and being able to manage the challenging movements, were related to positive experiences. In contrast, negative experiences were associated with not being able to perform the exercises, and with group members who dominated the conversational space. Conclusion: This study shows that access to a multimodal rehabilitation program with rhythm and music as operating ingredients may contribute to positive experiences for many individuals in a late phase after stroke in terms of motor, cognitive, as well as emotional enhancements. Important components were the music, the social interaction, the challenging exercises, and the skilled instructor.]]> Tue 03 Sep 2019 17:59:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33463 transformative experiences; human-horse interaction; togetherness and belonging; and the all-in-one solution. Interacting with the horse and peers had a profound emotional impact on the participants. The participants also reported having learned new skills, increased self-efficacy and self-esteem, and improvements in balance and gait, all of which could be transferred to everyday life. The horse itself played a central role, but other components, such as the other group members, the instructors, and the challenging tasks on the horseback, were also important. Conclusion: A multimodal rehabilitation intervention that includes horseback riding may provide stroke survivors in a late phase of recovery with rich pleasurable experiences that may have life-changing and profound impacts on their emotional and physical state.]]> Tue 03 Sep 2019 17:59:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35011 Thu 30 May 2019 15:05:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39917 Thu 30 Jun 2022 11:48:31 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36655 Thu 28 Oct 2021 13:04:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41049 Thu 21 Jul 2022 15:10:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33978 Thu 14 Apr 2022 11:04:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33090 Thu 13 Jan 2022 10:30:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33725 Thu 13 Jan 2022 10:30:08 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24213 Thu 09 Dec 2021 10:12:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30192 Thu 09 Dec 2021 10:11:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29940 Thu 04 Nov 2021 10:39:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33106 0.05). Conclusions: Stroke survivors with nonresolving fatigue reported reduced fatigue and improved quality of life after taking 200 mg daily treatment with modafinil.]]> Thu 03 Feb 2022 12:21:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48127 Thu 02 Mar 2023 15:41:40 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14102 Sat 24 Mar 2018 08:24:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14593 Sat 24 Mar 2018 08:20:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:10502 Sat 24 Mar 2018 08:08:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20933 Sat 24 Mar 2018 08:06:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20806 7-fold (hazard ratio 7.34, 95%, confidence interval 5.08-10.58) and a >8-fold (hazard ratio 8.44, 95%, confidence interval 4.64-15.37) increased risk of early-onset dementia and early-onset mild cognitive impairment, respectively. In conclusion, lower cardiovascular fitness and cognitive performance in early adulthood were associated with an increased risk of early-onset dementia and mild cognitive impairment later in life, and the greatest risks were observed for individuals with a combination of low cardiovascular fitness and low cognitive performance.]]> Sat 24 Mar 2018 08:05:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19926 Sat 24 Mar 2018 08:03:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20073 Sat 24 Mar 2018 08:00:11 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19115 Sat 24 Mar 2018 07:55:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19423 −/− Vim ^−/−) do not form cytoplasmic intermediate filaments. GFAP ^−/− Vim ^−/− mice develop larger infarcts after ischemic stroke (Li et al. in J Cereb Blood Flow Metab 28(3):468–481, 2008). Here, we attempted to analyze the underlying mechanisms using oxygen–glucose deprivation (OGD), an in vitro ischemia model, examining a potential link between astrocyte intermediate filaments and reactive oxygen species (ROS). We observed a reorganization of the intermediate filament network in astrocytes exposed to OGD. ROS accumulation was higher in GFAP ^−/− Vim ^−/− than wild-type astrocytes when exposed to OGD followed by reperfusion or when exposed to hydrogen peroxide. These results indicate that the elimination of ROS is impaired in the absence of the intermediate filament system. Compared to wild-type astrocytes, GFAP ^−/− Vim ^−/− astrocytes exposed to OGD and reperfusion exhibited increased cell death and conferred lower degree of protection to cocultured neurons. We conclude that the astrocyte intermediate filament system is important for the cell response to oxidative stress induced by OGD followed by reperfusion.]]> Sat 24 Mar 2018 07:51:56 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26114 Sat 24 Mar 2018 07:41:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28612 p=0.01); the higher body mass index was partially explained by PTHP (R² change=0.07, p=0.001). Otherwise no significant correlation was found among PTHP, functioning, or patient-reported quality of life. This study—which is unique in the homogeneity of the patients, the long follow-up time, and the use of injury severity as an outcome predictor—did not confirm results from previous studies linking PTHP to a worse outcome. Therefore, screening for PTHP might be restricted to specific subgroups such as overweight patients, indicating growth hormone deficiency.]]> Sat 24 Mar 2018 07:38:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28601 IGF1 locus could also associate with both IS and s-IGF1. We investigated whether genetic variation at the IGF1 locus is associated with i) s-IGF1, ii) IS occurrence, iii) IS severity, and iv) post-stroke outcome. Design/methods: Patients (n=844; 66% males, mean age 56 years) and community controls (n=668) were included from the Sahlgrenska Academy Study on Ischemic Stroke (SAHLSIS). Post-stroke outcome was evaluated with the modified Rankin Scale at 3 and 24 months after index stroke, and baseline stroke severity with the Scandinavian Stroke Scale. s-IGF1 was determined in patients and after random selection in 40 of the controls. Results: Eleven single nucleotide polymorphisms (SNPs) were selected in the IGF1 gene. In healthy controls the major allele of rs7136446 was associated with higher s-IGF1, whereas in patients no such association was found. No SNP was associated with IS, nor with stroke severity. After multivariate correction for presence of diabetes, smoking, and hypertension, the major allele of rs7136446 was associated with favorable functional outcome 24-months post-stroke (odds ratio 1.46; 95% CI 1.09–1.96). Conclusion: Variation in rs7136446 of the IGF1 gene associates with post-stroke outcome in relatively young IS patients. Also, rs7136446 associates with s-IGF1 in controls but not in IS, which indicates that IS perturbs a normal genetic impact on s-IGF1 levels.]]> Sat 24 Mar 2018 07:37:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27724 Sat 24 Mar 2018 07:36:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27631 Sat 24 Mar 2018 07:34:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28856 Sat 24 Mar 2018 07:33:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29552 Sat 24 Mar 2018 07:33:10 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28942 p < 0.05), as defined by a marked elevation in GFAP expression, within all 13 sites assessed within the ipsilateral (lesioned) hemisphere. We further observed significant increases in GFAP expression (p < 0.05) in 9 of the 13 contralesional sites examined. This work underscores that both the ipsilateral and contralesional hemispheres, at sites distal to the infarct, are very active many weeks after the initial occlusion, a finding that potentially has significant implications for understanding and improving the regeneration of the damaged brain.]]> Sat 24 Mar 2018 07:31:25 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29939 Sat 24 Mar 2018 07:31:00 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22857 Sat 24 Mar 2018 07:16:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23865 4 h per night during the 4-week study.]]> Sat 24 Mar 2018 07:13:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23450 Sat 24 Mar 2018 07:13:02 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23195 Sat 24 Mar 2018 07:10:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38395 146.7 ng/ml). The s-IGF-I level was not associated with recurrent stroke (N=79) or death (N=44), although it correlated with recovery (r=0.12, P=0.035). In the regression analysis, s-IGF-I associated with recovery between 3 months and 7 years (but not between 2 and 7 years). The associations did not withstand adjustment for age and sex. For comparison, the corresponding associations between 3 months and 2 years withstood all adjustments. Conclusion: The association for s-IGF-I with long-term post-stroke recovery persists after 7 years, which is also reflected in the mRS score distributions at all time-points. The effects are however modest, and not driven by mortality or recurrent stroke.]]> Mon 29 Jan 2024 17:47:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33098 Mon 27 Aug 2018 12:12:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45971 Mon 26 Jun 2023 16:03:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31937 stroke may induce a neurodegenerative condition. Certainly, this is supported to some degree by the relatively high incidence of dementia after stroke. We begin this review by addressing the available research on human and rodent SND pathology after stroke. We next consider amyloid-β in the context of SND. We discuss what amyloid-β is, how is it made, and introduce some caveats on how amyloid-β measurements should be interpreted. In summary, we conclude that there is now robust pre-clinical evidence demonstrating the presence of amyloid disturbances at sites of SND after stroke. We find, however, that the human literature on the topic is more limited and further work is warranted. While the understanding of amyloid disturbances remains inconclusive in human studies, stroke clearly lead to the development of a neurodegenerative-like condition at the sites of SND, with prominent features such as death of neurons and gliosis]]> Mon 23 Sep 2019 13:48:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32795 Mon 23 Sep 2019 12:44:11 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49585 Mon 22 May 2023 12:22:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49536 Mon 22 May 2023 08:38:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42362 Mon 22 Aug 2022 14:08:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53248 Mon 20 Nov 2023 10:15:18 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18704 Mon 20 Jul 2015 17:48:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50094 Mon 17 Jul 2023 10:30:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47380 Mon 16 Jan 2023 13:46:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50905 Mon 13 Nov 2023 08:50:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43040 Mon 12 Sep 2022 12:10:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52271 Mon 09 Oct 2023 10:04:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31933 n = 25) and compared with healthy controls (n = 25). Perceived fatigue was measured before, during and after the test session, and some of the tests were administered with and without standardized auditory distraction. Executive function and complex attention performance were poorer among the patients compared to controls. Interestingly, their performance was not significantly affected by auditory distraction but, in contrast to the controls, they reported a clear-cut increase in mental tiredness, during and after the test session. Thus, patients with stress-related exhaustion manage to perform during distraction but this was achieved at a great cost. These findings are discussed in terms of a possible tendency to adopt a high-effort approach despite cognitive impairments and the likelihood that such an approach will require increased levels of effort, which can result in increased fatigue. We tentatively conclude that increased fatigue during cognitive tasks is a challenge for patients with stress-related exhaustion and plausibly of major importance when returning to work demanding high cognitive performance.]]> Mon 09 Apr 2018 10:08:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42851 Mon 05 Sep 2022 15:40:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42735 Fri 30 Jun 2023 12:50:12 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30579 max) immediately prior to the 1 hour of task-specific training with the therapist. Recruitment, adherence, retention, participant acceptability, and adverse events will be recorded. Clinical outcome measures will be performed pre-randomisation at baseline, at completion of the training program, and at 1 and 6 months follow-up. Primary clinical outcome measures will be the Action Research Arm Test (ARAT) and the Wolf Motor Function Test (WMFT). If aerobic exercise prior to task-specific training is acceptable, and a future phase 3 randomised controlled trial seems feasible, it should be pursued to determine the efficacy of this combined intervention for people after stroke.]]> Fri 24 Aug 2018 09:07:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51912 Fri 22 Sep 2023 10:40:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40655 Fri 22 Jul 2022 14:02:02 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53133 Fri 17 Nov 2023 11:23:28 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38033 Fri 15 Jul 2022 10:39:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41794 Fri 12 Aug 2022 12:17:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37036 Fri 03 Dec 2021 10:32:41 AEDT ]]>